Home » CBD and Drug Interactions: An Easy Guide

CBD and Drug Interactions: An Easy Guide

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**IMPORTANT: CBD AND DRUG INTERACTIONS ARE NOT A JOKE. IF YOU WANT TO START TAKING CBD AND ARE ALREADY TAKING OTHER MEDICATIONS, PLEASE CHECK WITH YOUR DOCTOR FIRST!**

While CBD is safe to use, it can potentially mess with other medications you may be taking.

This quick guide should be all you need to safely use CBD even if you have other medications you need to take.

Can CBD interact with other drugs?

Yes. The way that CBD is metabolized by your body can interfere with how your body normally metabolizes other drugs you take. If those other drugs arn’t metabolized properly, they can hang around and stay in your system longer than you want. This can cause negative side effects and complications.

One kind of drug you should pay special attention to is a blood thinner like warfarin. Taking CBD with warfarin can make the warfarin stay in your system for too long without being broken down.

CBD drug interactions arn’t always bad. They can actually be a good thing. CBD can make other drugs more effective, so much so that you can reduce the dosage of those other drugs and thus have less negative side effects to deal with.

Read about how Alex reduced his epilepsy medication (under doctor supervision) by using CBD.

The Grapefruit Test is all you need

Thank you to Martin Lee of Project CBD for inspiring the Grapefruit Test. If you haven’t been to Project CBD yet, make sure to check it out. They are running a great site with lots of useful information about cannabis medicine.

As Lee explained in his class CBD 101, CBD interacts with other medications in your body in the same way as grapefruit, only even stronger.

grapefruit 154469 640

Have you ever been told not to take your medication with grapefruit? This is because compounds in grapefruits can interfere with the metabolism of many medications.

CBD does the same thing. But as I said above, the effect is even stronger with CBD.

Do the grapefruit test with your doctor or pharmacist. Ask them: “Should I avoid eating grapefruits or drinking grapefruit juice with this medication?”

They will know exactly what you are talking about. If they say yes, you should avoid grapefruits with your medication, you now know you need to be careful about mixing CBD with those same meds as well. Talk to your doctor about CBD and tell them about it if they say you should avoid grapefruits with your medication.

Useful links for CBD and drug interactions

Cannabis Drug Interactions

RxList on Grapefruit and Drug Interactions

Drug Interactions with Grapefruit Juice

Wikipedia: Grapefruit Drug Interactions

Washington D.C.’s Department of Health Medical Cannabis Slide Deck (look for the sections on CBD drug interactions)

Alternatively, you can skip the Grapefruit Test and just directly tell your doctor you want to use CBD.

We always recommend you do this anyway, even if your doctor doesn’t work with cannabis. Medical schools don’t educate physicians about the endocannainoid system, the most widespread receptor system in the human body. But that doesn’t mean we shouldn’t educate them about it!

If your doctor is aware of your CBD usage, he may decide to monitor your blood work more closely or tell you to avoid taking CBD at the exact same time as your other medications.

Play it safe and keep CBD safe. If you take other drugs, make sure they won’t interact negatively with CBD before you start taking CBD.

~ Vadim the CBD Professor

Summary
How CBD reacts when it interacts with other Drugs?
Article Name
How CBD reacts when it interacts with other Drugs?
Description
CBD has activated interactions with other Drugs too. It's really important to know how it reacts & what are reactions.
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Publisher Name
CBD School
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    • Hey Julie. Thanks for your question. I think CBD oil is definitely worth a try if you have epilepsy. But I always recommend checking with your doctor first and working alongside their supervision, especially if you are taking other medication already for epilepsy. Please let me know if you have other questions and I will do my best to help 🙂

      • if your doctor doesn’t know anything about CBD ask him about eating grapefruit or drinking grapefruit juice with your medication. also ask your pharmacist the same question. If they say no then do not, repeat do not take CBD oil.

        • Hi Linda. Thank you for your comment. We agree this is a good place to start the discussion with your doctor or pharmacist. We call it the “Grapefruit Test.”

          Still we recommend discussing CBD use openly in addition to discussing the Grapefruit Test. It’s better to be open about the desire to use CBD because there may be a situation where a doctor can have you use it and simply monitor your blood levels to determine if there is any negative drug interaction to be concerned about.

          We say this in order to prevent someone missing out on the potential benefits of CBD 🙂

          Would love to hear your thoughts!

    • I don’t remember the name of the seizure disorder that can be extremely bad in infants but the FDA just approved CBD for that type of epilepsy. That makes the first medication that was approved for this type. With the disorder I am talking about for some reason antiseizure medications resulted in more seizures.

      Just be careful because some of what I read was basically if you took too little CBD it would usually do nothing or rarely made the epilepsy worse. However, if you took enough CBD than it would help. I know that sounds backwards and like I am confused but I am writing it correctly.

      You should look up Charlotte’s Web which is a stronger CBD. That is what got the FDA to approve CBD for that particular infant epilepsy. It is also what is prompting the FDA recommendation for CBD to be researched further when it comes to Epilepsy. The down side is that there is no money to be made from getting CBD clinical trials for Epilepsy done so it’s not likely to be officially approved or researched for Epilepsy anytime soon.

      Clinical trials are very expensive and drug companies usually pay for them but there’s no money in CBD for them. We have the same problem with getting clinical trials done for Ketamine for depression. Ketamine is a cheap genetic drug and again there’s no money in it for any drug company so it sits there being used off-label and not officially FDA approved despite Ketamine being placed on the Fast Track for approval.
      The problem with it not being officially FDA approved for a disease is that there isn’t an insurance company in the world that will pay for it then.

      I am no doctor but if I had epilepsy I would try it. But I think you should do some reading of your own first and not just take my word for it. Remember when I said CBD at lower doses could make it worse? I don’t think they know exactly why but what they are thinking is that CBD makes your current medications less effective and at the same time the CBD dose is too low to have an affect on any seizure behavior. I would much rather have you do your research and a more thorough search then I did because at the time it wasn’t Epilepy that I was interested in or was even looking up.

      It was pain and depression so I wasn’t hanging onto the Epilepsy details. Charotte’s Web was what I was interested in and that when I starting reading the Epilepsy stuff. So please, please research this first without just taking my word for it. You might even come across more detailed information and maybe even a suggested dose. Again, please don’t just take my word for it. I only wrote what I wrote because I know things are looking good for Epilepsy but like I said it seems like it might be a slippery slope finding the CBD sweetspot for Epilepsy. Good Luck and I hope (after you research it yourself) that it works great for you! Take Care.

    • I haven’t heard of the cantab tablets but have heard great things about CBD pure. I take and sell HempWorx and live in KY whuch is a heavily opiate addicted state. I want to educate people on how CBD can help, especially with the Feds closing the doors on several pain clinics lately. The doctors who are “helping” these misplaced patients find solutions will not mention CBD and it is so frustrating. Congratulations on getting free of opiates. I used Suboxone which was harder to come off of than the opiates, especially cold turkey. Message me if you have any advice on how I can reach some of these patients without sounding like I just want to sell my product to them.
      Best Wishes,
      Jennifer

      • I also have tried coming off Suboxone which is indeed the most difficult of opiates to come off of. I’m currently starting on CBD for this as well as chronic pain and depression which caused all of this use. Any suggestions on disease and strength, etc. ? Thanks

  • Hi,

    Do you know of information about interactions with blood thinners specifically, metoprolol or where I can find the information?

    Thank you

    • Hey Kristin. Thanks for your question. I wish I could answer that but it’s completely outside my realm of expertise. My vet of choice for these types of questions is Gary Richter. He is a well experienced veterinarian who has a lot of experience working with CBD. Make sure to Google him and I bet he can answer you question. I hope that helps and please let me know if you have any other questions 🙂

    • Hey Marty. Thanks for your question. Unfortunately I do not know the answer as I am not a veterinarian. My veterinarian of choice who has a lot of experience working with cannabis is Dr. Gary Richter. You may also be able to ask your vet this question and get an answer. I hope that helps.

      • I sell Hempsey. They carry drops for pets. Probably depends on symptoms whether it helps or not. It’s been my experience that right now Drs. ( vets also ) don’t have a lot of CBD knowledge. My Dr. said give it a try…. CBD people say just go slow and build from there.

  • Have you heard of unwanted side effects for taking cbd oil with biologics and methotrexate? I know it may change the way my body metabolizes the meds I take and I have to have frequent blood-work for my liver & kidney function. The biologics and methotrexate have become less effective, either due to progression of my disorder or because my body has become resistant over the past 10 years. I’m in constant, severe pain, looking for relief where ever it may be found.

    • Hey Mrs. Storkey. Thanks for your inquiry. Unfortunately I cannot answer that as I am not a doctor. Please check with your doctor or pharmacist. What I can tell you is that most people do not have problems with drug interactions and CBD. Still I urge you to be cautious and check with a medical professional. Let me know please if there is anything else I can help you with 🙂

    • Hey John. Thanks for your question. Unfortunately I cannot answer this as I am not a doctor. Please check with your doctor or pharmacist. What I can tell you from my anecdotal experience is that most people do not have problems with drug interactions and CBD. Still I urge you to be cautious and check with a medical professional. Let me know please if there is anything else I can help you with 🙂

  • I had a Cortisone injection in my left knee on 25/4/18 will I suffer any ill effects if I take CBD oil?

    • Hey William. Good question, I haven’t had that one before. Remember I am not a doctor so my opinion is not professional. I would not think this would cause any problems but the best thing to do is just check with your doctor first. Let them know why you want to take the CBD and just make sure it’s OK to take alongside anything else you may be taking as well as the Cortisone injection. I’ve had those injections before as well. I hope you found relief from them. Let me know if you have any other questions I can do my best to help answer for you 🙂

  • I couldn’t eat grapefruit whilst I was on statins, but have stopped statins by doctor as they didn’t agree with me. I take other heart meds, I wonder if they would interfer with the CDB.

    • Hey Morag. I would definitely get this checked with your doctor. Let your doctor know you are taking CBD and you want to make sure it’s ok with your other medications. Let me know if you have other questions and I’ll do my best to help.

  • Can you recommend any veterinarians in the Seattle area that are familiar with the use of CBD oil? I recently adopted an older dog with hypothyroidism, arthritis, and muscle atrophy in his hind legs. Here’s a bit of a mess to say the least. Two weeks ago I started him on CBD oil (NuLeaf) after watching your videos. He’s at 5 drops, twice a day now and weighs about 90 pounds and is still under weight. He seems extra tired and grumpy the last few days and I’m wondering if the oil could be affecting his thyroid medicine. I would like to find a holistic vet to treat his pain and arthritis. Any recommendations would be appreciated,
    thanks, Claudia

    • Hey Claudia. Thanks for your inquiry. I have no way to know if it’s interacting with his other medicine as I’m not a vet. But it’s a good thing to get checked out so I’m glad to hear you asking this question. I know a very good vet in the SF Bay area named Dr. Gary Richter. It’s possible he may be able to do a phone consultation with you. Dr. Richter is who I would recommend. Sorry to hear about your pup, I know that’s frustrating. If you are consistently noticing a negative side effect with him after using CBD, it may not be the right tool for him. Let me know if you have other questions and I will do my best to help 🙂

  • I have a sick wife that has Asthma & leukemia , my question is she is on alot of medicine and I need to know if CBD will help her be herself again or close so she can go out and have a life .

    • Hey Hector. Thanks for your inquiry. I am sorry to hear about your wife. I cannot help you with this inquiry since I cannot provide medical advice. I urge you to please discuss this and get the OK from your doctor before using CBD.

  • Hi there
    Just started the CBD last week.
    5 mgs a day.
    I also have been and still am on a strong med called oxycodone.
    Have had croniv back pain for over 10 yrs. Really serious fibro for over 30 yrs.
    And lupus.
    I also take lerica.
    I’m going to try and decrease these horid perscribed meds.
    I have cronic pain most of the day and night.
    One week with CBD , but no difference as of yet .
    Is there something wrong I’m doing,?
    Is it just time or increase CBD dosage?
    Thanks.
    P.s. I am scared to ask my Dr. He’s against all canibis products.

    • Hey Debbie. Thanks for your inquiry and clear explanation. I appreciate that. Sorry to hear about the pain. I know that it’s hard. As long as you feel comfortable, you can increase the CBD dose to see if that would help. Keep in mind if it’s really intense pain, CBD may not be effective enough as a painkiller. However 5mg is generally considered a small dose. Sorry to hear your doctor isn’t open to it. But it’s just because it’s not FDA approved. I think this will change soon. Since you’re using multiple medications, I recommend you still get the OK from your doctor to use CBD. Please let me know how else I can help and I’ll do my best 🙂

  • If CBD is built up in your system over a few days, can the residual still have an effect on how p450 metabolizes drugs? I have been taking Ambien for sleep and tried CBD. Took a large dose one day (30mg) and 5mg 2x the following day. I ended up feeling drugged all day the following 2 days. Rather than the 10 or we hours Ambien is supposed to stay in your system.

    CBD supposedly stays in your system 3-5 days. I’m wondering if the residual could still have an effect on the Ambien.

  • Can I take CBB oil with my norco for post lisfranc foot surgery pain? I feel it will help wth the inflammation of the trauma. The pain meds are not that effective and I am struggling with the pain, my dr didn’t really have an opinion either way….

    • Hey Blu. Thanks for your question. Sorry to hear about your situation. I don’t have an answer to your question as I’m not a doctor. I would speak again to your doctor about it and or get a second opinion from a different doctor. You can speak with your pharmacist as well.

  • Hi Vadim,

    I won’t ask whether I can safely take CBD oil with my meds because I know (and you’ve repeatedly said) that you’re not a doctor or a pharmacist. I appreciate your ethics in that regard. I wish people would stop asking you to comment outside your scope of expertise. Don’t they know that if you advise them on such things it would endanger all the work you’re doing?

    The question I do have is whether or not you can comment on how long it might take to notice the effects of CBD usage? I have just begun (today) my CBD oil usage and I’m not sure how to decide that I’ve tried it at a certain dosage long enough and should change the dose. Is it, generally speaking, something I would notice right away (say, an hour after dosing) might it take a day or two to notice effects?

    Thanks!

    • Hey, thanks for your comment. I appreciate you understanding why I cannot provide medical advice. I’m happy to help with your question based on my own experience with CBD. First off, it will typically depend on what delivery method you’re using. How are you taking it, in this case?

      • Oh sorry! Stupid if me not to give you all the information. I’m taking a .5mL dose of an olive oil + CBD oil tincture. The label says it’s 500+mg in a 60mL bottle. I’ve only had one dose but the label says I’m able to take 1 to 4 doses, twice per day. I’m trying to take particular notice of any alteration to my symptoms (I have Parkinson’s and PTSD) in order to determine how much/often I should dose. Tentatively, I can say that I’ve been a bit happier since taking that first dose (I experience quite a bit of anxiety) but that may be wishful thinking. My goal in CBD use is to reduce anxiety, which has become quite debilitating. If I have positive effects in other ways, so much the better. My psychiatrist reacted positively when I asked about CBD usage and didn’t hesitate to recommend a “green card” for medical marijuana. However, I don’t like the experience of being high, so I chose CBD instead.

        • Great, thanks for the detailed information. One more question. What’s the serving size mg of CBD per dose? It sounds as if you are taking a typical serving size. I am pleased to hear you are working on this alongside a medical doctor. As long as you’re comfortable and with your doctor’s awareness, you can decide if you want to increase the dose gradually. Most people experiment slowly until they find their sweet spot and what works best for them. CBD is generally pretty subtle so I’m not surprised that you’re not feeling anything drastic. With an oral dose the effects are typically felt within 1 hour. Let me know if you have more questions and I will do my best to help.

  • Hi, I was wondering why the THC is needed at all. All new to me and I am considering using CBD oil for low grade aches/pains from exercise, but mostly for sleep disturbance (wakefulness). When I looked on the Project CBD website it mentioned something to the effect that the goal was to find the right dosage of CBD with ‘as much THC as a person is comfortable with’…
    My question is if the effects of CBD are enhanced with THC (or lessened w/o THC)?

    • Hello Tammy. Thanks for your excellent question. THC is not absolutely necessary. Some evidence has shown that THC and CBD work well together – this is the theory of the entourage effect. However plenty of people have good results using THC or CBD separately. THC can have some side effects which people do not like. It’s all about finding what works best for you, as each person’s case is different. As always, we recommend speaking with your doctor before using CBD or THC.

  • Hi me again, I have two other questions wondering if you can clarify to any degree. I have read some of the research lit on CBD and other articles that extrapolate this info, but I do not have a clear idea on two particular facets:
    1. CBD is known to affect the human cytochrome P450 system, at what dosage or level does this occur? Much of the research lists extremely high dosage levels.. many, many mg/kg – not near the recommended levels of use I have seen for general dosing. Is there a known level where the effects on the P450 system begin to occur in humans?
    2. Can or does CBD use lead to a tolerance whereby increasing doses are needed for the same effects – or not?

    TY

  • I have successfully slowly weaned myself off Palexia (an Opiod) by using CBD oil. However, my pain level is high at present (hot weather isn’t helping). I am prescribed Solpodol and Paracetamol and when taking Palexia I seldom needed them! I really need to know exact detail of the CBD oil for my severe Fibromyalgia, CFS and 2 buldging discs. Can you help me please? Thank you.

    • Hey Joy. Thanks for your comment. I’m not able to answer medical questions. But I can help you with general questions about CBD oil. Please consult with your doctor regarding medical questions and before using CBD oil. Thanks.

  • Know u can’t give specific answers, but in your experience does the reaction between warfarin and cbd any less when taken at different times. My husband has significant arthritis problems and benign tremors and would benefit from trying cbd but also must take warfarin due to having a 16 inch blood clot. Is it worth the risk? Thanks

  • CAN I TAKE CDB OIL WITH CODEINE OR AMYTRIPTYLINE .OR IF NOT, PROBABLY NOT.CAN I TAKE IT IF I THINK ITS GOING OUT OF MY SISTEM.

  • Don’t mix Clonazepam & CBD at any dose. Study has been done on anti-seizure drugs for CBD liver enzyme interactions. I found out the hard way as I was using CBD to taper off Zoloft (no interactions) and it helped tremendously until I suffered exploding head syndrome and was diagnosed with severe anti-depressant discontinuation syndrome and had to go back on 50mg Zoloft to stop the major brain lightening strikes. Also had to go back on clonazepam so I could sleep until zapping stopped. I never stopped taking CBD (30mg 25:1). Unfortunately Clonazepam is one of the meds that doesn’t get backed up in the blood waiting for CDB to stop inhibiting CYP 3a4 enzyme (only enzyme that metabolizes clonazepam) anywhere form 0 to 30% is excreted. So I started on a roller coaster of one day being fine then having benzo withdrawal the next day. Once I figured it out and stopped CBD it took a few days to get better as CBD has a long half life so it can take 3-5 days until you get a static blood level of clonazepam.

    https://www.projectcbd.org/science/cannabis-pharmacology/cbd-drug-interactions-role-cytochrome-p450. Scroll to bottom and hit link “AED Possible interatcions with CBD”.

    • Hi Laura. Thank you for your question. Please speak to your doctor before using CBD. Using CBD topically would be less likely to cause an interaction as compared to using CBD internally. Still it’s important to speak to your doctor about CBD because I cannot provide medical advice. Best of luck to you.

  • been told to 15%CBD OIL AND 15% HEMP OIL PLUS SUPPOSITORIES AT NIGHT, FOR PROSTATE CANCER, BUT NOT SURE IF THIS IS THE RIGHT DIRECTION?
    what equivalent has CBD brother in stock?

  • Out of all the questions people have asked you seem to have the same answer. That is you don’t know consult your doctor repeatedly the same answer over and over again. So tell me what is the purpose of your site. ?

    • Hey Rich. Thanks for your question. CBD School is an information resource for all things CBD, hemp, and cannabis. I can’t answer medical questions. But I will always help as much as I can, with product related questions mostly. Thanks for visiting and have a great day 🙂

  • Does TOPICAL CBD have any contraindications or drug interactions? I.e if I got a CBD infused Massage do I have to worry about anything?

    • Hey Tanya. Thanks for your excellent question. No, you should not have to worry about any interaction with a medication you are taking since the topical CBD from the massage is not entering your bloodstream. The only interaction to be possibly concerned with is with something else you are using on your skin, though I never heard of anyone having a problem with this. Let me know if you have any follow up questions 🙂

  • I have m s & a degenerative spine, also severe knee & hip pain. My pain killers do not work. I am also diabetic on Metformin. I am desperate to have less continuous pain. My g p does not know & said speak to my pharmacist. I am very keen to start on CBD+ oil. What can I do? Thank you.

    • Hello Sara. Thanks for your comment. I agree with your doctor. It would be best to speak with your pharmacist as they know all of your current medications. They may be able to suggest a different time of day for when to take the CBD so that it doesn’t interact with your other medications. You pharmacist and doctor may also want to monitor you while you take the CBD to make sure there are no negative interactions with the medications you are currently taking.

  • Thank you for sharing such a important information, as rarely people know this use of CBD. I know about CBD but not aware the CBD can be use in this way as well.

    • Hey Matt. Thanks for your question. It’s important to be careful about using CBD with Warfarin. We advise speaking to a doctor before starting. The problem is that CBD can alter the normal way your body processes the Warfarin, thereby changing its effects. Please speak with your doctor before using CBD if you are taking Warfarin. Your doctor may want to monitor you closely if you decide to use CBD to make sure there are no issues with a drug interaction.

  • I take two meds for prostate ,desmopressin tab and finasteride tab.do these two conflict with cbd. I have arthritis and was thinking about cbd for pain.

  • Hi
    I had a disc fusion level 4-5 2 years ago and have been left with chronic pain in my neck which no medication seems to relieve I am on 3 different medications one being diazepam do you think I could try hemp oil while using these drugs
    Any information would be very useful to me
    Thanks
    Debbie

    • Hi Debbie. Thanks for your comment. There is a possibility for a drug interaction between CBD and your other medications. I urge you to check with your doctor first as they may want to monitor your blood levels of other medications you are on. Project CBD just released an excellent paper on drug interactions which you should download and check out. It’s on their website for free download.

    • Hi thanks for your question. Please speak to your doctor or pharmacist about this. Project CBD has also released a new report on drug interaction for 2018 which we highly recommend you check out. Visit Project CBD to download the report.

    • Hello Dona. Thanks for your question. CBD may interact with pain medications. Some people find this interaction beneficial because it allows them to take less of their opiate medications and avoid side effects and addiction to the opiate pain killers. Still I recommend you speak with a doctor and your pharmacist first, before using CBD. I also recommend you review the brand new report just published over at Project CBD on drug interactions. You can go to the Project CBD website and download it for free. Let me know if you have more questions please.

    • Hey Isobel. Thanks for your question. Unfortunately we at CBD School do not have the medical background to answer specific questions. My recommendation is to speak to a doctor or pharmacist for this specific inquiry.

      For an additional resource, Project CBD has recently released a comprehensive report entirely on CBD and drug interactions. You can find that on Project CBD’s website and download the report for free. It’s a good resource.

  • Can I safely take CBD oil with these prescription drugs:
    Citalopram 10mg
    Propranolol 40mg
    Lanoprozole
    Clopidogrel 75mg
    Paracetamol 500mg
    Thanks in advance
    Oliver

    • Hey Oliver. Thanks for your question. Unfortunately we at CBD School do not have the medical background to answer specific questions. My recommendation is to speak to a doctor or pharmacist for this specific inquiry.

      For an additional resource, Project CBD has recently released a comprehensive report entirely on CBD and drug interactions. You can find that on Project CBD’s website and download the report for free. It’s a good resource.

  • I have been sober for over 25 years. I was in a car accident and broke my neck/back, tore several abdominal organs as well as lost 1/2 right lung. Currently take meds for several GI problems, CTE, COPD, Hashimotos, I get cortisone/steroids (alternate) shots directly to knees, shoulders, neck, lower back as well as epidural shots for spinal cord injury on a scale 1-10, I live with a 7 daily pain level and yes I also suffer from PTSD. (tired just writing it all). I’ve avoided drinking CBD Living water but my son gave me a case for my birthday. ….. will drinking the water help me lessen the pain? Which is the primary trigger of my PTSD. …. is the water addicting? …. will I be breaking my sobriety? Will it get me high?

    • Hey Nury. Thanks for your comment and question. CBD is non-addictive and non-intoxicating. It isn’t used recreationally but people to like to use it to relax since it often has an anti-anxiety and calming effect. Many people report that CBD does help with their pain. For the condition you are describing, it may require more CBD than what’s contained in the CBD Water. A more concentrated CBD product example would be a tincture or a capsule. I recommend you speak with a medical professional who knows your current medications before you start using CBD. Best of luck. And let us know if you have more questions and we will do our best to help 🙂

    • Hey Shar. Thanks for your question. Unfortunately we at CBD School do not have the medical background to answer specific questions. My recommendation is to speak to a doctor or pharmacist for this specific inquiry about this medication and CBD.

      For an additional resource, Project CBD has recently released a comprehensive report entirely on CBD and drug interactions. You can find that on Project CBD’s website and download the report for free. It’s a good resource.

    • Hey Eileen. Thanks for your question. Unfortunately we at CBD School do not have the medical background to answer specific questions. My recommendation is to speak to a doctor or pharmacist for this specific inquiry about this medication and CBD.

      For an additional resource, Project CBD has recently released a comprehensive report entirely on CBD and drug interactions. You can find that on Project CBD’s website and download the report for free. It’s a good resource.

    • Hey Lisa. Thanks for your question. Unfortunately we at CBD School do not have the medical background to answer specific questions. My recommendation is to speak to a doctor or pharmacist for this specific inquiry about this medication and CBD.

      For an additional resource, Project CBD has recently released a comprehensive report entirely on CBD and drug interactions. You can find that on Project CBD’s website and download the report for free. It’s a good resource.

    • Hey Sian. Thanks for your question. Unfortunately we at CBD School do not have the medical background to answer specific questions. My recommendation is to speak to your doctor or a pharmacist for this specific inquiry about this medication and CBD.

      For an additional resource, Project CBD has recently released a comprehensive report entirely on CBD and drug interactions. You can find that on Project CBD’s website and download the report for free. It’s a good resource.

  • Glad I read this I take Wartharin and I’d herd it could effect my INR dint no it made Wartharin stay in your blogs longer no wonder they’ve been all over place with my blood reading or/INR same to I just won some grate stuff !!

    • Hi Denise. Thanks for your comment and question. Many people do find that CBD helps them be less anxious. There are indeed some theories that CBD may have to build up in your system to get the most benefits. However I have never seen any evidence for this. It doesn’t mean it’s not true. Hope that helps 🙂

  • I’m taking Metformin, Rosuvastatin, Lisinopril, Triamterene, Amlodipine Besylate, and Escitalopram Oxalate. Any known drug interactions with these and CBD oil?

    • Hey Lee. Thanks for your question. Unfortunately we at CBD School do not have the medical background to answer specific questions. My recommendation is to speak to your doctor or a pharmacist for this specific inquiry about this medication and CBD.

      For an additional resource, Project CBD has recently released a comprehensive report entirely on CBD and drug interactions. You can find that on Project CBD’s website and download the report for free. It’s a good resource.

    • Hey Ford. Thanks for your question. Unfortunately we at CBD School do not have the medical background to answer specific questions like the one you asked. My recommendation is to speak to your doctor or a pharmacist for this specific inquiry about this medication and CBD.

      For an additional resource, Project CBD has recently released a comprehensive report entirely on CBD and drug interactions. You can find that on Project CBD’s website and download the report for free. It’s a good resource.

  • I have a friend who has the autoimmune condition Lupus, and wanted to try CBD oil to treat it. I got him a bottle, but he was reluctant to take it because:
    A. He wanted to discuss the issue with his doctor, but keeps forgetting to mention the issue during his last visit.
    B. The oil that I got for him was mixed with coconut oil, which he is allergic to because of his Lupus condition.
    C. He told me that he takes Warfarin, and is concerned about possible interactions with it.
    What should I advise him. Would CBD oil be appropriate for him?

    • Hi Robert. Thanks for your great questions. It’s good that your friend has someone like you to help him. I answered your questions below. Please write me back if you have more! 🙂
      A. Yes, he absolutely needs to discuss this with his doctor first.
      B. There are plenty of CBD products out there without coconut oil. Bluebird Botanicals CBD tincture is just one example. They use hemp seed oil instead of coconut oil.
      C. He absolutely needs to check with his doctor first. The doctor may request to monitor his blood levels while he takes the CBD to make sure there is no negative interaction with Warfarin. Please be careful about this. Always talk to the doctor before starting CBD.

      For an additional resource, Project CBD has recently released a comprehensive report entirely on CBD and drug interactions. You can find that on Project CBD’s website and download the report for free. It’s a good resource. This would be good to show his doctor.

      Let me know if you have more questions! 🙂

    • Hey Connie. Thanks for your question. Unfortunately as much as our mission is to do our best to get all your CBD questions answered, we at CBD School do not have the medical background to answer specific questions like the one you asked.

      My recommendation is to speak to your doctor or a pharmacist for this specific inquiry about this medication and CBD.

      For an additional resource, Project CBD has recently released a comprehensive report entirely on CBD and drug interactions. You can find that on Project CBD’s website and download the report for free. It’s a good resource.

    • Hello Marilynn. Thanks for your question. While it’s still a good idea to inform your doctor you will be adding CBD products into your wellness routine, I don’t think you need to worry about a drug interaction when using topical CBD. The drug interactions which have been studied all occurred when CBD was ingested internally into the body. Hope that answers your question. Please do not hesitate to reach out if you have additional questions or concerns 🙂

    • Hey Gilda. Thanks for your question. Unfortunately as much as our mission is to do our best to get all your CBD questions answered, we at CBD School do not have the medical background to answer specific questions like the one you asked.

      My recommendation is to speak to your doctor or a pharmacist for this specific inquiry about this medication and CBD.

      For an additional resource, Project CBD has recently released a comprehensive report entirely on CBD and drug interactions. You can find that on Project CBD’s website and download the report for free. It’s a good resource.

    • Hey Ed. Thanks for your question. Unfortunately as much as our mission is to do our best to get all your CBD questions answered, we at CBD School do not have the medical background to answer specific questions like the one you asked.

      My recommendation is to definitely speak to your doctor or a pharmacist for this specific inquiry about using Xanax with CBD.

      For an additional resource, Project CBD has recently released a comprehensive report entirely on CBD and drug interactions. You can find that on Project CBD’s website and download the report for free. It’s a good resource.

  • Hi
    I started taking 6 drops, twice per day of CBD oil 3 days ago to help extreme back pain/ sciatica. I found I felt a bit weird, a bit woozy and tired after the third day. I take amlodipine for high blood pressure, levothyroxin for underactive thyroid and ibuprofen and paracetamol for the pain. Would CBD have this effect?
    I have been told to avoid grapefruit when taking amlodipine.

    • Hi Barbara. Thank you for your question. This is a serious matter and you need to seek the advice of a medical professional like a doctor or pharmacist. While we strive to do our best to answer as many questions as we can, we cannot help with medical questions like this.

      Please stop taking CBD and speak with your doctor immediately about this.

  • Hi.
    I’m on lots of medication to control my condition which is very complex. I have late on set Asthma. The GP has found this to be difficult to control with normal inhalers and now I take alot of medication. The main drug I take is sterroids and this drug has many side effects if taken over a long time are numerous and life long. Like Brittle Bones to name one, I’m sure you can name more. Its very hard to explain the pain associated with Brittle Bones and other conditions associated with sterroids. I took the sterroids over 20years. Like most when the pain started I took paracetamol and quickly moved onto other more effective meds until now where I’m on the maximum of morphine and sometimes I’m over the 150mg. I take this in 2 ways 100mg and 25mg fenanil patches and the rest topped up with oralmorph at regular intervals daily. I also take nefopam and paracetamol. Now I’m trying to reduce the sterroids to reduce my risk of complications from the bariatric surgery to support my lose of weight and eventually alleviate some of the symptoms of Asthma. I know all the complications like addiction and more from morphine and other pain meds. I want them to stop and go back to the person I used to be. I need to know the drug interactions so I can take CBD effectively. My GP will not tell me or look into CBD to give me any answers. He just shuts me down with “we can not, and will not, talk about CBD at all. If that’s what you would like to talk about, please leave”.

    Could u help? Would u like me to right Down the list of meds or would it be easier to show me the list CBD interacts with. I think it would be a lot smaller than my list of meds.

    Thank you

    Nikki
    (Nicolette Freeman AKA Sonnex)

    • Hi Nicolette. Thanks for your comment and question. At CBD School we strive to answer all the CBD questions we can. However we are not able to provide medical advice. In your situation I would recommend you seek out the help of a cannabis clinic and doctor who is able to provide medical advice for your specific condition and the use of CBD and cannabis.

  • Ok,
    These are my regular everyday drugs that I take.
    Please tell me if you see any problems with me using CBD and these medications. My major health issues are Rhumitoid Arthritis, Fibromyalgia, Osteoarthritis and my disc are collapsing.
    These are my meds
    Celebrex 200 mg twice a day
    Lyrics 100 mg twice a day
    DULoxetine 30 mg once a day
    Tramadol 100 mg as needed
    ( usually 2 to 3 times a day )
    Lorazepam 1 mg once or twice a day
    ORENCIA injection, Once a week

    • Hey Ruth. Thanks for your question. Unfortunately as much as our mission is to do our best to get all your CBD questions answered, we at CBD School do not have the medical background to answer specific questions like the one you asked.

      My recommendation is to speak to your doctor or a pharmacist for this specific inquiry about your medication and CBD.

      For an additional resource, Project CBD has recently released a comprehensive report entirely on CBD and drug interactions. You can find that on Project CBD’s website and download the report for free. It’s a good resource.

    • Hey Brandan. Thanks for your question. There are many CBD brands on the market offering a wide variety of products. Most brands differ in their product line and speciality items. It all depends on what you are looking for.

      For safe products, you want to find a brand which provides you with good customer support and up-to-date lab reports for their full product line. If you don’t see the lab reports on a brand’s website, you can call them and request them. They should provide them to you.

      For effectiveness, it’s difficult to predict as you will only know once you try a CBD product for yourself.

      I would be happy to check out some of the brands you’re considering and help you make a decision. We have some of our favorite brands listed here and you can also check out the reviews section of the site.

      Please let us know how else we can help you get your CBD questions answered 🙂

  • Can a person on blood thinners use CBD oil topically without complications internally? I know that I can’t take it internally.

    • Hi Martha. Thanks for your question. I recommend you still check this with your doctor or pharmacist but I see no issues with a drug interaction when using a topical CBD product like a balm or cream.

      There are unique topicals called “transdermals” and these are designed to be used on your skin (usually in the form of a patch) and permeate through the skin to enter the body. Those would possibly be a concern though I have never heard of someone having a drug interaction from those.

      If you are using CBD cream or balm, I do not see this as a problem. Of course we always recommend you get the final OK from a doctor or medical professional. Thanks 🙂

    • Hello James. Thanks for your comment. Since we are not able to provide medical advice or answer medical questions, we encourage everyone to consult their doctor about their questions before using CBD.

    • Hey Karen. Thanks for your question. Unfortunately as much as our mission is to do our best to get all your CBD questions answered, we at CBD School do not have the medical background to answer specific questions like the one you asked.

      My recommendation is to speak to your doctor or a pharmacist for this specific inquiry about your medication and CBD.

      For an additional resource, Project CBD has recently released a comprehensive report entirely on CBD and drug interactions. You can find that on Project CBD’s website and download the report for free. It’s a good resource. Here is another good resource to check out as well.

  • Please address taking CBD oil and anti-depressants. Please address taking CBD oil and opioids or painkillers. For example, I believe that the CBD oil renders the opioids virtually useless.

    • Hi Gary. Thanks for your comment and your insightful suggestions. Those are in the works.

      Will you please link to any sources or information regarding CBD oil rendering opioids useless?

      Thanks again for your contribution.

  • Hi I’m excited to find this where I can write a question and hopefully an answer, my name is Stephanie and I So Luckily was told about Hempworx CBD Oil 750mg!!
    I suffered from Chronic CONSTANT Pain in my Neck and Back, ( I’m 43 never been in any accident but I’ve been diagnosed with Herniated and Bulging Discs in my neck and back and full of Deterioration) that is why I was interested in the Oil!!
    I asked some questions to a woman that uses it and sells it and I purchased it right away!!
    In week 1 already saw the Enormous difference!! Pain is pretty much Gone!!!
    I never asked Doctors or Pharmacist until just recently and None of my Pharmacists know anything about CBD Oil and I went to see my Psychiatrist which I see because I have Bipolar, Depression, Anxiety, ADHD and Sleep Issues and I brought the bottle and showed him and told him I’ve been taking it for almost 1 month and my Awful Pain is basically gone!!
    Probably knowing it has some THC in it he joked with me and picked it up and pretended to drink it all but otherwise he said nothing about it!!
    Obviously I am on many Meds Prescribed from him and he is a young Physician Assistant and is pretty cool!!
    I used to be Prescribed 3 extended release Morphine 30mg but after the Law came out awhile ago the Dr. wouldn’t allow me to be on 3 a day and lowered me to 1 a day because I take Colonopins and the Strict law says a person CAN’T be prescribed a Painkiller and something like Colonopin which is known as Clonazepam together but he said he was doing me a favor by allowing me 1 Morphine a day!!
    Well I recently left Pain Management and weaned myself off the Morphine it did nothing anyway!!
    When I went to my Internal Medicine Dr. The other day I told her I take it and she said ABSOLUTELY Nothing!! Like she also didn’t know what it is!!
    So what do I do??
    Keep doing what I’ve been doing or what??
    Thanks

  • Two years ago I was diagnosed with Sarcoidosis after some severe food reactions. I was prescribed Prednisone. Can I take islolated CBD oil drops with Prednisone?

  • I am hoping to take the cannabis. I have severe neck and back problems where I cannot walk without a walker and cannot do housework,clean floors, etc My pain doctor told me that if I quit taking the prescribed I would be bedridden andmcouldn’t get Out of bed. I take my maximum amt. nd I have gotten immured to the amount I was taking. I need to get off them completely. I wish it was a Dr.that specialzes I’m mess.

    • Hi Carol. Thanks for your comment. I completely understand your situation. Please do listen to your doctor as they know your condition better than us. We are not able to provide any medical advice but I can help you get connected with a cannabis clinician. What area do you live in? Happy to help in any way we can 🙂

    • Hi Diane. Thanks for your great question. We get this question a lot! We might do a full article on this in the future so watch for that! Using CBD topically should not result in any drug interactions. The only exception may be with a topical transdermal product which is designed to enable the CBD to permeate the skin and get into the blood stream. Please let us know if you don’t understand what transdermal CBD products are and we will be happy to help. In addition, although CBD is not known to cause any drug interactions when used topically, we still do recommend you check with your doctor to make sure CBD products are appropriate for you, based on your unique situation. Make sure to let us know if you have any additional questions 🙂

  • I’m on morphine- time release pills, for 12 back surgeries, as in chronic pain!!
    Reading this oil or a tablet might get me off the opiates? I’ve told my doc I want offfff….life not the same on that crap, and I have been for many years.
    Guess no one’s listening?

  • I have fybromyalgia and other conditions and am on tramadole and ropinarole and lanzoprozole and and levothroxine and paracetomole and asthma inhaylas and was thinking of trying cbd oil but don’t know how to start whith the meds do i stop or carry on whith the med and try the oil I have been on meds for years and hate taking them and have had fybro for approx 17 pluses years can you help

    • Hi Joanne. Thanks for your comment and question. We cannot make any medical advice or recommendations on what to do with your current medications. Please speak to a trusted medical professional about this.

      If you have CBD product questions, we will be happy to help with that 🙂

  • Terminology seems to be confusing when dealing with CBD
    CBD oil is a term used to describe hemp oil and marijuana all over the Internet. So I’m clear when ur saying CBD has a interaction with warafin can u be more specific whether u are talking about hemp oil or marijuana oil or both

    • Hi Carol. Thanks for your great question. We get this question a lot! We might do a full article on this in the future so watch for that! Using CBD topically (in a cream or balm) should not result in any drug interactions.

      The only exception may be with a topical transdermal product which is designed to enable the CBD to permeate the skin and get into the blood stream. Please let us know if you don’t understand what transdermal CBD products are and we will be happy to help.

      In addition, although CBD is not known to cause any drug interactions when used topically, we still do recommend you check with your doctor to make sure CBD products are appropriate for you, based on your unique situation. Make sure to let us know if you have any additional questions 🙂

  • I want to use hemp oil, not ingested but topical, for both arthritis and drop foot. I take meds for high bp, cholesterol, and depression. Will this interfere with it

    • Hello and thanks for your great question. We get this question a lot! We might do a full article on this in the future so watch for that! Using CBD topically (in a cream or balm) should not result in any drug interactions.

      The only exception may be with a topical transdermal product which is designed to enable the CBD to permeate the skin and get into the blood stream. Please let us know if you don’t understand what transdermal CBD products are and we will be happy to help.

      In addition, although CBD is not known to cause any drug interactions when used topically, we still do recommend you check with your doctor to make sure CBD products are appropriate for you, based on your unique situation. Make sure to let us know if you have any additional questions 🙂

  • Can you take cbd oil with levothyroxine (thyroid), cellcept (for lung issue that hopefully I’m odd in next 6 months). Zoloft & I’m being weaned off prednisone, down to 5 MG for 2 weeks, then 2.5

  • Is cbd from marijuana the one that metabolizes and interacts with meds or is it the cbd from hemp oil? Or both?
    I’m confused because cbd from hemp oil only contains a small amount of cbd compared to marijuana cbd.

    • Hi Donna. Thanks for your great question. CBD from marijuana and CBD from hemp are the same. They can both result in a drug interaction. Please consult with a doctor before using CBD if you are already using other medicines.

    • Hi Michael. Thanks for your question. We at CBD School cannot provide answers to any medical related questions. Please speak to a doctor or pharmacist about these questions. Thanks for understanding.

  • Can CBD oil be taken with turmeric? Or how about a menopausal supplement that contains Don Quai, milk thistle, black cohosh and chamomile?

  • Hiya, looking for advice on dealing with Lumbar and Cervical Spine pain after road accident. Artritis has also set in after year’s of degenerative wear. I don’t use pain killers as they have a negative impact on my system.

  • I’m taking Amitripyline for migraines and to help sleep. Also take sumatriptan on the on start of a migraine. I have arthritis as well in feet and I am awaiting appointment with rheumatology to see if arthritis in hands. Would I be able to take CBD oil as well. Would like to reduce the amitripyline altogether in future if I could deal with migraines

  • So I recently got CBD for my dad to take due to that he has arthritis and he can’t sleep at night but he also takes linsinopril Atenolol and I wanted to know if it’s safe if he takes the cbds at night cause all his meds are taken in the mornign

    • Hi Janet. Thank you for your question. I completely understand why you are wanting to use this strategy. Unfortunately we don’t have the medical background to confirm if it’s the best way to go. I suggest you speak to your dad’s doctor/pharmacist for a final confirmation. They will be able to help you.

  • I have been taking a steroid nose spray. Should I not take the Cbd oil? If not how long should I wait after I stop the steroids can I use the oil.

  • I have chronic fatigue, a bleeding disorder (von willebrands disease) which requires me to get iron infusion about once per year, can I take CBD?

    • Hi Melissa. Thanks for your question. We’ve never encountered that question or heard of anyone having a problem with procedure and CBD. We recommend you check with your doctor to be on the safe side. Thanks 🙂

  • Thank you so much for this article. I went to my local CBD store to inquire about CBD oil and lotion for my father. The sales person assured me that there would be no drug interactions, but I researched anyway. I’m glad I did, as my dad is on blood thinners. I plan on printing this out and bringing it to the store to educate them.

    • Hi Deena. Thanks for your question. We cannot answer this question as we have no medical background. Since CBD has shown to interact with certain drugs, please speak to your doctor about this. Your doctor or pharmacist will be able to answer if there would be any problem with a drug interaction and CBD. Thanks for understanding.

  • I’ve had 7 operations on the same hip, the last in2011 and, am suffering significant pain. 3 Surgeons I’ve recently seen, refuse to do so again.
    I currently take co-codamol, Naproxen and down to one tablet a day of Tamsulosin 400mg following a prostate cancer op in March last year.
    Will CBD oil relieve the pain ?
    I will also put this question to my doctor, as I see you recommend

    • Hi Champion Peter. Thanks for your comment and question. Sorry to hear about your hip. It’s good to hear you are working alongside your doctor and he has knowledge if your interest in CBD. It’s impossible for me or you to know if CBD will help until you try using it. So as long as your doctor and you agree it’s safe to try, my opinion is it’s worth a trial to see if it will work.

      Let us know if you have any additional questions 🙂

    • Hey Christi. Interesting question. Thanks for that! I’ve never had this question or researched this topic heavily. Cannabinoids are very well preserved in cold temperatures but can degrade in very hot temperatures.

      I am curious: why do you ask?

      Thanks for contributing 🙂

  • I take metoprolol tartrate after breakfast 25 mg. If I take the hemp oil first, how long do you think I should wait until I take the metoprolol 25mg.

  • I have been using THC CBD combination, equal amounts of both in a cartridge which has helped me sleep soundly. But in the last month I have been experiencing insomnia and it does not seem to help. I have taken valium in small doses previously which usually put me to sleep so I could get back to a normal sleep cycle. When I ran out I went to my doctor ( a differnt doctor) who prescribed trazadone because she said valium can cause dementia in older patients such as myself. I asked her if I could use cannabis when taking the trazodone and she said yes. However the trazodone hasn’t worked as well even though she recommended increasing the dosage which doesn’t seem to help either. So I am wondering if decreasing the dosage of trazodone and increasing my intake of THC CBD will help me sleep better.

    • Hey Tom. Thanks for your comment and sharing your story. Sorry to hear it’s not working as well for you at the moment.

      You could certainly experiment with the dosage of THC/CBD to see if that would help. A different product or delivery method might work well too.

      Since your doctor already knows you are using cannabis and CBD and has approved, we recommend you discuss this with her as well. She knows your medical history and will be the best person to get feedback from about changing dosages or delivery methods.

      Let us know if you have any more questions. Thanks 🙂

  • I am taking Xanax and blood pressure medications. Is it safe for me to take CBD? Thanks…I would love to take it for my depression and Fibromyalgia….

  • My son 16 has in the past been on halaperidol strattera and Zoloft. You prob know what happened. Made him suicidal and depressed. So I got him off and started using cbd oil. But he developed vocal tics which the cbd didnt seem to help. So he is taking 2mg of the haliperidol (only thing that helps although I hate him taking it) So does the CBD interact ? I haven’t seen any negative but I’d like to get him off that too. Maybe I’m not giving him enough of the dosage? He’s been on the Cbd for over a year now and it has helped with the depression / anxiety – but with the tics it doesn’t seem to be handling it. Any advice. P.S. his Dr. Won’t even discuss CBD oil. Doesn’t exist in his world. So dead end there. He rather give him more pills. Help!

    • Hey Judy. Thanks for your comment and questions. Our best advice is to seek out a doctor or medical provider for your son who is open to discussing CBD and the best way to use it. Thanks for understanding that we cannot provide medical advice at CBD School.

  • I am currently using blood pressure medications, tribenzor and 50 mgs of metatropolol succinate….I have started taking 25 mgs cbd oil and it has helped with some arthritis pain as i have two artificial hips… my question is will 25 mgs of cbd oil affect my blood pressure meds thanks

  • cbd with d.m.s.o. is what I use for my joints, back, knees
    and so on I find the pain goes away for two days.
    Have you ever looked into this?

    • Hi Mary Ann. Thanks for your question.

      We cannot provide any medical advice on the topic of what a person can or cannot take with CBD. We can tell you that we have never heard of anyone having any drug interaction issues with Tylenol and CBD.

      For the best answer to your question, please consult with a trusted doctor or pharmacist. Thank you for understanding.

    • Hi Char. Thanks for your question. The answer is it’s impossible to know until you try the CBD for the pain. We recommend you discuss it first with your doctor to make sure taking CBD is appropriate for you.

  • Hi -I am currently taking lots of ibuprofen to manage pain in my shoulder due to adhesive Capulitis (frozen shoulder). I want to start 15 mg cbd capsules. Have take. 1 for the last few nights without the ibuprofen but am in so much pain. Can I take ibuprofen with the cbd capsule?

    • Hi Daisy. Thanks for your question. We have never heard of someone having a problem taking CBD along with ibuprofen. You should consult with a trusted medical provider about this before taking it. Thank you for understanding we are not able to provide any medical advice 🙂

  • In mid-January for the first time, I acquired Shingles. The rash only lasted about 2 weeks but I am one of the unfortunate ones who was left with postherpetic neuropathy. EXTREMELY PAINFUL, and I am told, can last for weeks, months or years.
    I am in so much pain. My PCP started me on Lyrica, used off-label for this, however when I read about CBD, it said not to use it with an anti-epileptic medication. This is after I ordered the topical cream from Charlotte’s Web.
    My question is — does the topical cream have the same effect on oral medications as the oral form does?

    • Hi Tara. Thanks for your great question.

      You should check out this article where we wrote about drug interaction and topical CBD.

      Topical products do not generally cause problems with drug interactions. Still, to be absolutely sure, we recommend you check with doctor about this inquiry. Best of luck! 🙂

  • Can you take Plavix blood thinner with Full Spectrum CBD Hemp oil? I have read that it can be dangerous. Thanks

  • I take meloxicam 15g two days a week. Can I take cbd oil .I take the meloxicam for shoulder tear and some arthritis

  • HI, I am writing today because no one can seem to give me an answer.

    I am a stage 3c Inflammatory breast cancer survivor.

    I take daily – 12.5 mg Hydrochlorothiazide for high blood pressure and 25 mg of Exemestane.

    In December I started taking a 1:1 ratio of CBD/THC gummies (10 mg) and starting using a suave with the same dosage. My Oncologist said it was okay and the Medical Marijuana Doctor says it is okay but I read otherwise online….

    I am at a lost as to were to turn for educated advice….PLEASE HELP!!!!

    • Hi Christy. Thanks for your message. Our best recommendation is to consult with your trusted medical professionals as we lack the medical background required. Thank you for understanding.

  • Hey there… Love the School!
    New here trying to understand it all as there is so much info out here and it can be confusing. I apologize if someone else has asked this ~

    If taking CBD orally with other medications I keep reading to take 3 to 4 hours apart. So for example: I take Lyrica for neuropathy 12 hours apart.

    So.. Would I take the CBD at say like 6 hours apart to be in the middle?

  • This is very useful information since the effect of grapefruit on medication are well know.

    In my case:
    Amlodipine : CBD oil slow down the elimination of the drugs which increase the effect so it may lower blood pressure more than expected.

    Lozartan: CBC oil reduce the effect so it may not reduce blood pressure as expected.

    I take CBD oil for Crohn Disease to reduce the activity of digestive track, reduce spasm, reduce anxiety, reduce pain. Initial dosage 5mg CBD with spray 3 times a day.

    I will talk with my doctor about effect of CBD oil on my blood pressure medication and see how it can be adjusted.

  • My understanding is that if you use drops and let them absorb under your tongue, it doesn’t metabolize in your liver and the issue becomes moot, as far as the grapefruit test goes.

  • Can I vape cbd oil? I take 50mg of toprol in the morning and 25mg of toprol at night. Originally I started taking toprol for my anxiety & heart palpitations I only had high blood pressure once at the doctors Office so he raised it. What affect will it cause? My doctor knows nothing about cbd & refused to give me any advice

    • Hi Jessica. Thanks for your comment. We can’t answer your question as we’re not able to provide that type of consultation. We know it’s frustrating when you can’t get an answer from your doctor. We recommend finding another medical professional who can answer your question about using CBD with your other medications.

  • Im bipolar, have trouble sleeping, wake very early every day. On Lamotrogin and clonazlpam, will cbd clash?

  • Hiya my dad is taking chlopidrol it a blood thinner, and his on larcanidipine for blood pressure. Is it safe to take cbd oil with these medications.

  • Hi i’m taking a blood thinner called Apixaban Which I cannot get on with have tried others as well, someone suggested taking cannabis oil as a natural blood thinner, I wonder whether you could help me with this.

    • Hi Grenville. Thanks for your comment. We are not able to help with medical related questions as we do not currently have a medical trained professional on staff. We recommend doing more research and also consulting with a medical provider who is well experienced with cannabis. Thanks for understanding.

  • I started taking cbd oil, wanted to know if it will affect the effectiveness of taking propecia for hair loss. Been on propecia for 2 years.

    • Hi Kalpesh. That’s a very good question. Unfortunately we don’t know the answer. We have never heard of anyone having a problem with this. Thanks and best of luck to you 🙂

  • I take fiorinal #3 with Codeine have u heard of any problems when taking cbd oil ty what’s ur answer then please

  • I have bad knee pain from 2 surgeries and some arthritis. Will topical CBD effect my talking warfarin for valve replacement. Not sure how often I would need to use it for the toothache in my knee.

  • Is topical cbd oil absorbed into the system the same as sublingual? I want my husband to try it for chronic knee pain but he is on warfin.

    • Hi Donna. Thanks for your question. Topical CBD does not work the same way as sublingual and would likely not be absorbed as much. However no study comparing the two to one another has ever been done (that we know of). Generally, it’s considered that sublingual product would absorb more CBD. If you husband is on Warfarin and still decides to use CBD, we recommend speaking to his doctor as his doctor can monitor his blood level to make sure everything is OK. Thank you.

  • Hi, I have Interstitial Cystitis, Pelvic Floor Dysfunction and Lichen Sclerosis; along with anxiety, Depression, ADHD, and Fibromyalgia. I presently take Clobetasol Propionate ointment for the Lichen Sclerosis but wanted to try taking CBD oil for the other conditions and was wondering if taking both CBD oil and Clobetasol Propionate ointment is ok, and if not, what are the negative effects?

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